Microplate Lids
Cayman Chemical ThIol GlutathIon Stndard 1ea
A polyamine bile amidate has been used as a standard for the detection of endogenous bile acid amidates in mammalian fecal samples
Cayman Chemical ThIoglycerol Stndard 0.1mL
A disulfide bond-containing ionizable cationic lipid has been used in the generation of LNPs for plasmid delivery in vitro and in vivo LNPs containing PPPDA-O16B and encapsulating plasmids encoding RRSP increase RRSP levels and decrease Ras levels in and reduce the viability of HeLa cancer cells LNPs containing PPPDA-O16B and encapsulating plasmids encoding RRSP selectively localize to tumors over the heart liver spleen lungs and kidneys as well as decrease tumor volume without reducing body weight in an HCT116 colorectal cancer mouse xenograft model
Cayman Chemical NItrIte Stndard 1ea
A GCGR GLP-1R and GIP receptor agonist induces cAMP accumulation in HEK293 cells expressing the human GCGR GLP-1R or GIP receptor (EC50s 5.79 0.775 and 0.0643 nM respectively) decreases plasma glucose levels in an intraperitoneal glucose tolerance test in mice from 0.1-30 nmol/kg decreases body weight calorie intake fat mass and lean mass in a mouse model of diet-induced obesity acute administration delays gastric emptying and chronic administration for 10 days decreases food intake and body weight in mice
Cayman Chemical Hydrogen PeroxIde Stndard 1ea
Source Recombinant human TEAD4 cofactor-binding domain expressed in insect cells Amino acids 217-434 MW 25.5 kDa
Cayman Chemical Pyruvate asy Stndard 1ea
An internal standard for the quantification of psilocybin by GC- or LC-MS provided as a DEA exempt preparation intended for research and forensic applications
Cayman Chemical MorphIn ELISA Stndard 1ea
An internal standard for the quantification of ADB-5Br-BUTINACA by GC- or LC-MS intended for research and forensic applications
Cayman Chemical tetrnor-PGDM ELISA Stndard 1ea
A cationic lipid has been used for transfection of DNA RNA and other negatively charged molecules into eukaryotic cells has been used in the composition of small unilamellar liposomes formulated as gene delivery vectors for gene therapy
Cayman Chemical CyclIc GMP ELISA Stndard 1ea
An ionizable cationic lipidoid has been used in the generation of LNPs LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce CCl4-induced liver fibrosis in mice
Cayman Chemical CyclIc AMP ELISA Stndard 1ea
An ionizable cationic lipidoid has been used in the generation of LNPs LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce the expression of Hsp47 in activated NIH3T3 mouse liver fibroblasts and primary mouse hepatic stellate cells LNPs containing AA-T3A-C12 and encapsulating Hsp47 siRNA reduce CCl4-induced liver fibrosis in mice
Cayman Chemical 96-Wel Cover Sheet 5ea
A multi-kinase inhibitor selectively inhibits MET VEGFR2 Axl and Mer (IC50s 3 15 5.8 and 0.6 nM respectively) over serine/threonine kinases for which it has no activity but does inhibit 28 additional RTKs (IC50s 3-54 nM) and additional kinases by greater than 70 at 1 UM inhibits the proliferation of SNU-5 cells (IC50 98.9 nM) and HUVECs (IC50 10.4 nM) reduces tumor volume and intratumoral MET phosphorylation in NCI H441 and SNU-5 mouse xenograft models at 3 and 10 mg/kg increases the number of peripheral B cells and CD4 T cells and decreases the number of peripheral myeloid cells in an MC-38 syngeneic mouse model of colon carcinoma at 30 mg/kg